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The complex structure of bile salt hydrolase from Lactobacillus salivarius reveals the structural basis of substrate specificity

The gut bacterial bile salt hydrolase (BSH) plays a critical role in host lipid metabolism and energy harvest. Therefore, BSH is a promising microbiome target to develop new therapies to regulate obesity in humans and novel non-antibiotic growth promoters for food animals. We previously reported the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Xu, Fuzhou, Hu, Xiao-Jian, Singh, Warispreet, Geng, Wenjing, Tikhonova, Irina G., Lin, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6711994/
https://ncbi.nlm.nih.gov/pubmed/31455813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48850-6
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