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Lactobacillus bile salt hydrolase substrate specificity governs bacterial fitness and host colonization

Primary bile acids (BAs) are a collection of host-synthesized metabolites that shape physiology and metabolism. BAs transit the gastrointestinal tract and are subjected to a variety of chemical transformations encoded by indigenous bacteria. The resulting microbiota-derived BA pool is a mediator of...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Foley, Matthew H., O’Flaherty, Sarah, Allen, Garrison, Rivera, Alissa J., Stewart, Allison K., Barrangou, Rodolphe, Theriot, Casey M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8017965/
https://ncbi.nlm.nih.gov/pubmed/33526676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2017709118
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