Fractalkine Induces Hepcidin Expression of BV-2 Microglia and Causes Iron Accumulation in SH-SY5Y Cells

Fractalkine (CX3CL1) is a potent inflammatory mediator of the central nervous system, which is expressed by neurons and regulates microglial functions by binding to fractalkine receptor (CX3CR1). It has been demonstrated that neuroinflammation plays an important role in iron accumulation of the brai...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Mol Neurobiol
Hauptverfasser: Pandur, Edina, Tamási, Kitti, Pap, Ramóna, Varga, Edit, Miseta, Attila, Sipos, Katalin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2019
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6711953/
https://ncbi.nlm.nih.gov/pubmed/31172340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10571-019-00694-4
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