Inhibition and assessment of the biophysical gating properties of GluA2 and GluA2/A3 AMPA receptors using curcumin derivatives

The development of efficacious and safe drugs for the treatment of neurological diseases related to glutamate toxicity has been a focus in neuropharmacological research. Specifically, discovering antagonists to modulate the activity and kinetics of AMPA receptors, which are the fastest ligand-gated...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Qneibi, Mohammad, Hamed, Othman, Natsheh, Abdel-Razzak, Fares, Oswa, Jaradat, Nidal, Emwas, Nour, AbuHasan, Qais, Al-Kerm, Rana, Al-Kerm, Rola
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6711591/
https://ncbi.nlm.nih.gov/pubmed/31454362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0221132
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