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SLC19A1 is an importer of the immunotransmitter cGAMP
2’3’-cyclic-GMP-AMP (cGAMP) is a second messenger that activates the antiviral Stimulator of Interferon Genes (STING) pathway. We recently identified a novel role for cGAMP as a soluble, extracellular immunotransmitter that is produced and secreted by cancer cells. Secreted cGAMP is then sensed by h...
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| Publicat a: | Mol Cell |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6711396/ https://ncbi.nlm.nih.gov/pubmed/31126740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.05.006 |
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