Surprising synergy of dual translation inhibition vs. Acinetobacter baumannii and other multidrug-resistant bacterial pathogens

BACKGROUND: Multidrug-resistant (MDR) Acinetobacter baumannii infections have high mortality rates and few treatment options. Synergistic drug combinations may improve clinical outcome and reduce further emergence of resistance in MDR pathogens. Here we show an unexpected potent synergy of two trans...

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Bibliographic Details
Published in:EBioMedicine
Main Authors: Dillon, Nicholas, Holland, Michelle, Tsunemoto, Hannah, Hancock, Bryan, Cornax, Ingrid, Pogliano, Joe, Sakoulas, George, Nizet, Victor
Format: Artigo
Language:Inglês
Published: Elsevier 2019
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Research paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6711115/
https://ncbi.nlm.nih.gov/pubmed/31353294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.07.041
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