Surprising synergy of dual translation inhibition vs. Acinetobacter baumannii and other multidrug-resistant bacterial pathogens

BACKGROUND: Multidrug-resistant (MDR) Acinetobacter baumannii infections have high mortality rates and few treatment options. Synergistic drug combinations may improve clinical outcome and reduce further emergence of resistance in MDR pathogens. Here we show an unexpected potent synergy of two trans...

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Dettagli Bibliografici
Pubblicato in:EBioMedicine
Autori principali: Dillon, Nicholas, Holland, Michelle, Tsunemoto, Hannah, Hancock, Bryan, Cornax, Ingrid, Pogliano, Joe, Sakoulas, George, Nizet, Victor
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019
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Research paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6711115/
https://ncbi.nlm.nih.gov/pubmed/31353294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.07.041
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