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Assessment of Antibody Interference of Enfuvirtide (T20) Function Shows Assay Dependent Variability
BACKGROUND: During HIV infection, fusion of the viral and cellular membranes is dependent on folding of the gp41 trimer into a six-helix bundle. Fusion inhibitors, such as the antiretroviral Enfuvirtide (T20), interfere with the formation of the gp41 six-helix bundle. Recent in vitro studies reveal...
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| Publicado no: | Curr HIV Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Bentham Science Publishers
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6710457/ https://ncbi.nlm.nih.gov/pubmed/30836922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570162X17666190228154850 |
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