PBPK Modeling-based optimization of site-specific chemo-photodynamic therapy with far-red light-activatable paclitaxel prodrug

Photodynamic therapy (PDT) is a clinically approved therapeutic modality to treat certain types of cancers. However, incomplete ablation of tumor is a challenge. Visible and near IR-activatable prodrug, exhibiting the combined effects of PDT and local chemotherapy, showed better efficacy than PDT al...

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Bibliografske podrobnosti
izdano v:J Control Release
Main Authors: Li, Mengjie, Nguyen, Luong, Subramaniyan, Bharathiraja, Bio, Moses, Peer, Cody J., Kindrick, Jessica, Figg, William D., Woo, Sukyung, You, Youngjae
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6710169/
https://ncbi.nlm.nih.gov/pubmed/31299262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2019.07.010
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