The distinct conformational landscapes of 4S-substituted prolines that promote an endo ring pucker

4-Substitution on proline directly impacts protein main chain conformational preferences. The structural effects of N-acyl substitution and of 4-substitution were examined by NMR spectroscopy and X-ray crystallography on minimal molecules with a proline 4S-nitrobenzoate. The effects of N-acyl substi...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Costantini, Nicholas V., Ganguly, Himal K., Martin, Maxwell I., Wenzell, Nicole A., Yap, Glenn P. A., Zondlo, Neal J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6710147/
https://ncbi.nlm.nih.gov/pubmed/31237705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201902382
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