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Evaluation of pharmacokinetic modeling strategies for in-vivo quantification of tau with the radiotracer [(18)F]MK6240 in human subjects
PURPOSE: [(18)F]MK6240 was developed for PET imaging of tau aggregates which are implicated in Alzheimer’s disease. The goal of this work was to evaluate the kinetics of [(18)F]MK6240 and to investigate different strategies for in-vivo quantification of tau aggregates in humans. METHODS: Thirty-five...
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| Publicado no: | Eur J Nucl Med Mol Imaging |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6709592/ https://ncbi.nlm.nih.gov/pubmed/31332496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-019-04419-z |
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