Generalized concentration addition model predicts glucocorticoid activity bioassay responses to environmentally-detected receptor ligand mixtures

Many glucocorticoid receptor (GR) agonists have been detected in waste and surface waters domestically and around the world, but the way a mixture of these environmental compounds may elicit a total glucocorticoid activity response in water samples remains unknown. Therefore, we characterized 19 GR...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Toxicol Sci
Prif Awduron: Kakaley, Elizabeth Medlock, Cardon, Mary C., Gray, L. Earl, Hartig, Phillip C., Wilson, Vickie S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709530/
https://ncbi.nlm.nih.gov/pubmed/30535411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfy290
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