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High-Dose Ceftriaxone for Bacterial Meningitis and Optimization of Administration Scheme Based on Nomogram

High dosages of ceftriaxone are used to treat central nervous system (CNS) infections. Dosage adaptation according to the glomerular filtration rate is currently not recommended. Ceftriaxone pharmacokinetics (PK) was investigated by a population approach in patients enrolled in a French multicenter...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Grégoire, Matthieu, Dailly, Eric, Le Turnier, Paul, Garot, Denis, Guimard, Thomas, Bernard, Louis, Tattevin, Pierre, Vandamme, Yves-Marie, Hoff, Jérôme, Lemaitre, Florian, Verdier, Marie-Clémence, Deslandes, Guillaume, Bellouard, Ronan, Sébille, Véronique, Chiffoleau, Anne, Boutoille, David, Navas, Dominique, Asseray, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709482/
https://ncbi.nlm.nih.gov/pubmed/31235630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00634-19
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