Optimal Scheduling of Bevacizumab and Pemetrexed/Cisplatin Dosing in Non‐Small Cell Lung Cancer

Bevacizumab‐pemetrexed/cisplatin (BEV‐PEM/CIS) is a first‐line therapeutic for advanced nonsquamous non‐small cell lung cancer. Bevacizumab potentiates PEM/CIS cytotoxicity by inducing transient tumor vasculature normalization. BEV‐PEM/CIS has a narrow therapeutic window. Therefore, it is an attract...

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Detalhes bibliográficos
Publicado no:CPT Pharmacometrics Syst Pharmacol
Main Authors: Schneider, Benjamin K., Boyer, Arnaud, Ciccolini, Joseph, Barlesi, Fabrice, Wang, Kenneth, Benzekry, Sebastien, Mochel, Jonathan P.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709425/
https://ncbi.nlm.nih.gov/pubmed/31004380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12415
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