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Cbl-PI3K Interaction Regulates Cathepsin K Secretion in Osteoclasts

Effective bone resorption by osteoclasts is critical for balanced bone remodeling. We have previously reported that mice harboring a substitution mutation of tyrosine 737 to phenylalanine in the adapter protein Cbl (Cbl(Y737F), YF) have increased bone volume partly due to decreased osteoclast-mediat...

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Bibliografiske detaljer
Udgivet i:Bone
Main Authors: Yu, Jungeun, Adapala, Naga Suresh, Doherty, Laura, Sanjay, Archana
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708784/
https://ncbi.nlm.nih.gov/pubmed/31299383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2019.07.009
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