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Cbl-PI3K Interaction Regulates Cathepsin K Secretion in Osteoclasts
Effective bone resorption by osteoclasts is critical for balanced bone remodeling. We have previously reported that mice harboring a substitution mutation of tyrosine 737 to phenylalanine in the adapter protein Cbl (Cbl(Y737F), YF) have increased bone volume partly due to decreased osteoclast-mediat...
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| Vydáno v: | Bone |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6708784/ https://ncbi.nlm.nih.gov/pubmed/31299383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2019.07.009 |
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