A NOVEL PHENOTYPIC METHOD TO DETERMINE FLUDARABINE TRIPHOSPHATE ACCUMULATION IN T-LYMPHOCYTES FROM HEMATOPOIETIC CELL TRANSPLANTATION PATIENTS

PURPOSE: Fludarabine is an integral anticancer agent for patients with chronic lymphocytic leukemia (CLL) and those receiving conditioning regimens prior to allogeneic hematopoietic cell transplantation (HCT). An individual’s response to fludarabine may be influenced by the amount of CD4(+) and CD8(...

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Publicado en:Cancer Chemother Pharmacol
Autores principales: Woodahl, Erica L., Wang, Joanne, Heimfeld, Shelly, Sandmaier, Brenda M., O'Donnell, Paul V., Phillips, Brian, Risler, Linda, Blough, David K., McCune, Jeannine S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708594/
https://ncbi.nlm.nih.gov/pubmed/18398611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-008-0748-0
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