A NOVEL PHENOTYPIC METHOD TO DETERMINE FLUDARABINE TRIPHOSPHATE ACCUMULATION IN T-LYMPHOCYTES FROM HEMATOPOIETIC CELL TRANSPLANTATION PATIENTS

PURPOSE: Fludarabine is an integral anticancer agent for patients with chronic lymphocytic leukemia (CLL) and those receiving conditioning regimens prior to allogeneic hematopoietic cell transplantation (HCT). An individual’s response to fludarabine may be influenced by the amount of CD4(+) and CD8(...

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Udgivet i:Cancer Chemother Pharmacol
Main Authors: Woodahl, Erica L., Wang, Joanne, Heimfeld, Shelly, Sandmaier, Brenda M., O'Donnell, Paul V., Phillips, Brian, Risler, Linda, Blough, David K., McCune, Jeannine S.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708594/
https://ncbi.nlm.nih.gov/pubmed/18398611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-008-0748-0
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