Repurposing dasatinib for diffuse large B cell lymphoma

To repurpose compounds for diffuse large B cell lymphoma (DLBCL), we screened a library of drugs and other targeted compounds approved by the US Food and Drug Administration on 9 cell lines and validated the results on a panel of 32 genetically characterized DLBCL cell lines. Dasatinib, a multikinas...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Scuoppo, Claudio, Wang, Jiguang, Persaud, Mirjana, Mittan, Sandeep K., Basso, Katia, Pasqualucci, Laura, Rabadan, Raul, Inghirami, Giorgio, Grandori, Carla, Bosch, Francesc, Dalla-Favera, Riccardo
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2019
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708382/
https://ncbi.nlm.nih.gov/pubmed/31383760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1905239116
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