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MutComFocal: an integrative approach to identifying recurrent and focal genomic alterations in tumor samples

BACKGROUND: Most tumors are the result of accumulated genomic alterations in somatic cells. The emerging spectrum of alterations in tumors is complex and the identification of relevant genes and pathways remains a challenge. Furthermore, key cancer genes are usually found amplified or deleted in chr...

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Detalhes bibliográficos
Main Authors: Trifonov, Vladimir, Pasqualucci, Laura, Favera, Riccardo Dalla, Rabadan, Raul
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637169/
https://ncbi.nlm.nih.gov/pubmed/23531283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-7-25
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