Epithelial delamination is protective during pharmaceutical-induced enteropathy

Intestinal epithelial cell (IEC) shedding is a fundamental response to intestinal damage, yet underlying mechanisms and functions have been difficult to define. Here we model chronic intestinal damage in zebrafish larvae using the nonsteroidal antiinflammatory drug (NSAID) Glafenine. Glafenine induc...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Espenschied, Scott T., Cronan, Mark R., Matty, Molly A., Mueller, Olaf, Redinbo, Matthew R., Tobin, David M., Rawls, John F.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708343/
https://ncbi.nlm.nih.gov/pubmed/31391308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1902596116
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