Intense Light-Mediated Circadian Cardioprotection via Transcriptional Reprogramming of the Endothelium

Consistent daylight oscillations and abundant oxygen availability are fundamental to human health. Here, we investigate the intersection between light-sensing (Period 2 [PER2]) and oxygen-sensing (hypoxia-inducible factor [HIF1A]) pathways in cellular adaptation to myocardial ischemia. We demonstrat...

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Publicat a:Cell Rep
Autors principals: Oyama, Yoshimasa, Bartman, Colleen M., Bonney, Stephanie, Lee, J. Scott, Walker, Lori A., Han, Jun, Borchers, Christoph H., Buttrick, Peter M., Aherne, Carol M., Clendenen, Nathan, Colgan, Sean P., Eckle, Tobias
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708043/
https://ncbi.nlm.nih.gov/pubmed/31390562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.07.020
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