Intense light-elicited upregulation of miR-21 facilitates glycolysis and cardioprotection through Per2-dependent mechanisms

A wide search for ischemic preconditioning (IPC) mechanisms of cardioprotection identified the light elicited circadian rhythm protein Period 2 (Per2) to be cardioprotective. Studies on cardiac metabolism found a key role for light elicited Per2 in mediating metabolic dependence on carbohydrate meta...

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Bibliographic Details
Published in:PLoS One
Main Authors: Bartman, Colleen Marie, Oyama, Yoshimasa, Brodsky, Kelley, Khailova, Ludmila, Walker, Lori, Koeppen, Michael, Eckle, Tobias
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407766/
https://ncbi.nlm.nih.gov/pubmed/28448534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176243
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