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Inhibition of Bruton’s Tyrosine Kinase Modulates Microglial Phagocytosis: Therapeutic Implications for Alzheimer’s Disease

Bruton’s tyrosine kinase (BTK), a critical component of B cell receptor signaling, has recently been implicated in regulation of the peripheral innate immune response. However, the role of BTK in microglia, the resident innate immune cells of the central nervous system, and its involvement in the pa...

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Bibliographic Details
Published in:J Neuroimmune Pharmacol
Main Authors: Keaney, James, Gasser, Julien, Gillet, Gaëlle, Scholz, Diana, Kadiu, Irena
Format: Artigo
Language:Inglês
Published: Springer US 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6707957/
https://ncbi.nlm.nih.gov/pubmed/30758770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-019-09839-0
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