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Inhibition of Bruton’s Tyrosine Kinase Modulates Microglial Phagocytosis: Therapeutic Implications for Alzheimer’s Disease

Bruton’s tyrosine kinase (BTK), a critical component of B cell receptor signaling, has recently been implicated in regulation of the peripheral innate immune response. However, the role of BTK in microglia, the resident innate immune cells of the central nervous system, and its involvement in the pa...

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Detalhes bibliográficos
Publicado no:J Neuroimmune Pharmacol
Main Authors: Keaney, James, Gasser, Julien, Gillet, Gaëlle, Scholz, Diana, Kadiu, Irena
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6707957/
https://ncbi.nlm.nih.gov/pubmed/30758770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-019-09839-0
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