Elevated insulin and insulin resistance are associated with altered myelin in cognitively unimpaired middle-aged adults

OBJECTIVE: Insulin regulates metabolism and influences neural health. Insulin resistance (IR) and type II diabetes have been identified as risk factors for Alzheimer’s disease (AD). Evidence also suggests that myelinated white matter alterations may be involved in the pathophysiology of AD; however,...

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Detalhes bibliográficos
Publicado no:Obesity (Silver Spring)
Main Authors: O’Grady, J Patrick, Dean, Douglas C, Yang, Kao Lee, Canda, Cristybelle-Marie, Hoscheidt, Siobhan M., Starks, Erika J, Merluzzi, Andrew, Hurley, Samuel, Davenport, Nancy J, Okonkwo, Ozioma C, Anderson, Rozalyn M, Asthana, Sanjay, Johnson, Sterling C, Alexander, Andrew L, Bendlin, Barbara B
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6707894/
https://ncbi.nlm.nih.gov/pubmed/31314172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.22558
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