Plasmid-encoded tet(X) genes that confer high-level tigecycline resistance in Escherichia coli

Tigecycline is one of the last-resort antibiotics to treat complicated infections caused by both multidrug-resistant (MDR) Gram-negative and Gram-positive bacteria1. Tigecycline resistance has sporadically occurred in recent years, primarily due to chromosome-encoding mechanisms, such as overexpress...

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Publicado no:Nat Microbiol
Main Authors: Sun, Jian, Chen, Chong, Cui, Chao-Yue, Zhang, Yan, Liu, Xiao, Cui, Ze-Hua, Ma, Xiao-Yu, Feng, You-Jun, Fang, Liang-Xing, Lian, Xin-Lei, Zhang, Rong-Min, Tang, You-Zhi, Zhang, Kou-Xing, Liu, Han-Mian, Zhuang, Zhi-Hui, Zhou, Shi-Dan, Lv, Jing-Nan, Du, Hong, Huang, Bin, Yu, Fang-You, Mathema, Barun, Kreiswirth, Barry N., Liao, Xiao-Ping, Chen, Liang, Liu, Ya-Hong
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6707864/
https://ncbi.nlm.nih.gov/pubmed/31235960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-019-0496-4
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