Genetic compensation triggered by mutant mRNA degradation

Genetic robustness, or the ability of an organism to maintain fitness in the presence of mutations, can be achieved via protein feedback loops. Recent evidence suggests that organisms may also respond to mutations by upregulating related gene(s) independently of protein feedback loops, a phenomenon...

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Библиографические подробности
Опубликовано в: :Nature
Главные авторы: El-Brolosy, Mohamed A., Kontarakis, Zacharias, Rossi, Andrea, Kuenne, Carsten, Günther, Stefan, Fukuda, Nana, Kikhi, Khrievono, Boezio, Giulia L.M., Takacs, Carter, Lai, Shih-Lei, Fukuda, Ryuichi, Gerri, Claudia, Giraldez, Antonio J., Stainier, Didier Y.R.
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6707827/
https://ncbi.nlm.nih.gov/pubmed/30944477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1064-z
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