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Proteotoxic stress reprograms the chromatin landscape of SUMO modification

The small ubiquitin-like modifier 2 (SUMO-2) is required for survival when cells are exposed to treatments that induce proteotoxic stress by causing the accumulation of misfolded proteins. Exposure of cells to heat shock or other forms of proteotoxic stress induces the conjugation of SUMO-2 to prote...

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Publicat a:Sci Signal
Autors principals: Seifert, Anne, Schofield, Pietà, Barton, Geoffrey J., Hay, Ronald T.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6707813/
https://ncbi.nlm.nih.gov/pubmed/26152697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaa2213
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