Screen for multi-SUMO–binding proteins reveals a multi-SIM–binding mechanism for recruitment of the transcriptional regulator ZMYM2 to chromatin

Protein SUMOylation has emerged as an important regulatory event, particularly in nuclear processes such as transcriptional control and DNA repair. In this context, small ubiquitin-like modifier (SUMO) often provides a binding platform for the recruitment of proteins via their SUMO-interacting motif...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Aguilar-Martinez, Elisa, Chen, Xi, Webber, Aaron, Mould, A. Paul, Seifert, Anne, Hay, Ronald T., Sharrocks, Andrew D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
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PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568223/
https://ncbi.nlm.nih.gov/pubmed/26283374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1509716112
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