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Characterization of the pharmacology, signal transduction and internalization of the fluorescent PACAP ligand, fluor-PACAP, on NIH/3T3 cells expressing PAC1
Fluor-PACAP, a fluorescent derivative of PACAP-27, has been confirmed to share a high affinity for PAC1 receptors transfected into NIH/3T3 cells and to have comparable pharmacological characteristics to the unconjugated, native form. Through competitive binding with (125)I-PACAP-27, the two ligands...
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| Udgivet i: | Peptides |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6707527/ https://ncbi.nlm.nih.gov/pubmed/11390014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/s0196-9781(01)00410-7 |
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