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Classification of the nucleolytic ribozymes based upon catalytic mechanism

The nucleolytic ribozymes carry out site-specific RNA cleavage reactions by nucleophilic attack of the 2′-oxygen atom on the adjacent phosphorus with an acceleration of a million-fold or greater. A major part of this arises from concerted general acid–base catalysis. Recent identification of new rib...

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Bibliografiske detaljer
Udgivet i:F1000Res
Hovedforfatter: Lilley, David M.J.
Format: Artigo
Sprog:Inglês
Udgivet: F1000 Research Limited 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6707401/
https://ncbi.nlm.nih.gov/pubmed/31489181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.19324.1
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