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The structure of a nucleolytic ribozyme that employs a catalytic metal ion
The TS ribozyme (originally called twister-sister) is a nucleolytic catalytic RNA. We present a crystal structure of the ribozyme in a pre-reactive conformation. Two co-axial helical stacks are organized by a three-way junction and two tertiary contacts. Five divalent metal ions are directly coordin...
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| Udgivet i: | Nat Chem Biol |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5392355/ https://ncbi.nlm.nih.gov/pubmed/28263963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2333 |
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