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Chemical probes and drug leads from advances in synthetic planning and methodology

Screening of small-molecule libraries is a productive method for identifying both chemical probes of disease-related targets and potential starting points for drug discovery. In this article, we focus on strategies such as diversity-oriented synthesis that aim to explore novel areas of chemical spac...

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Detalhes bibliográficos
Publicado no:Nat Rev Drug Discov
Main Authors: Gerry, Christopher J., Schreiber, Stuart L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6707071/
https://ncbi.nlm.nih.gov/pubmed/29651105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd.2018.53
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