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Inactivation of a Mismatch-Repair System Diversifies Genotypic Landscape of Escherichia coli During Adaptive Laboratory Evolution

Adaptive laboratory evolution (ALE) is used to find causal mutations that underlie improved strain performance under the applied selection pressure. ALE studies have revealed that mutator populations tend to outcompete their non-mutator counterparts following the evolutionary trajectory. Among them,...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Kang, Minjeong, Kim, Kangsan, Choe, Donghui, Cho, Suhyung, Kim, Sun Chang, Palsson, Bernhard, Cho, Byung-Kwan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6706779/
https://ncbi.nlm.nih.gov/pubmed/31474949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.01845
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