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Three New Scorpion Chloride Channel Toxins as Potential Anti-Cancer Drugs: Computational Prediction of The Interactions With Hmmp-2 by Docking and Steered Molecular Dynamics Simulations

Scorpion venom is a rich source of toxins which have great potential to develop new therapeutic agents. Scorpion chloride channel toxins (ClTxs), such as Chlorotoxin selectively inhibit human Matrix Methaloproteinase-2 (hMMP-2). The inhibitors of hMMP-2 have potential use in cancer therapy. Three ne...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Iran J Pharm Res
Prif Awduron: Baradaran, Masoumeh, Jalali, Amir, Naderi Soorki, Maryam, Jokar, Mahmoud, Galehdari, Hamid
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Shaheed Beheshti University of Medical Sciences 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6706747/
https://ncbi.nlm.nih.gov/pubmed/31531056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22037/ijpr.2019.1100659
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