Three New Scorpion Chloride Channel Toxins as Potential Anti-Cancer Drugs: Computational Prediction of The Interactions With Hmmp-2 by Docking and Steered Molecular Dynamics Simulations

Scorpion venom is a rich source of toxins which have great potential to develop new therapeutic agents. Scorpion chloride channel toxins (ClTxs), such as Chlorotoxin selectively inhibit human Matrix Methaloproteinase-2 (hMMP-2). The inhibitors of hMMP-2 have potential use in cancer therapy. Three ne...

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Detalles Bibliográficos
Publicado en:Iran J Pharm Res
Autores principales: Baradaran, Masoumeh, Jalali, Amir, Naderi Soorki, Maryam, Jokar, Mahmoud, Galehdari, Hamid
Formato: Artigo
Lenguaje:Inglês
Publicado: Shaheed Beheshti University of Medical Sciences 2019
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6706747/
https://ncbi.nlm.nih.gov/pubmed/31531056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22037/ijpr.2019.1100659
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