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CLIC4 regulates late endosomal trafficking and matrix degradation activity of MMP14 at focal adhesions in RPE cells

Dysregulation in the extracellular matrix (ECM) microenvironment surrounding the retinal pigment epithelium (RPE) has been implicated in the etiology of proliferative vitreoretinopathy and age-related macular degeneration. The regulation of ECM remodeling by RPE cells is not well understood. We show...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Hsu, Kuo-Shun, Otsu, Wataru, Li, Yao, Wang, Heuy-Ching, Chen, Shuibing, Tsang, Stephen H., Chuang, Jen-Zen, Sung, Ching-Hwa
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6706427/
https://ncbi.nlm.nih.gov/pubmed/31439888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48438-0
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