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The Late Endosomal Pathway Regulates the Ciliary Targeting of Tetraspanin Protein Peripherin 2

Peripherin 2 (PRPH2) is a tetraspanin protein concentrated in the light-sensing cilium (called the outer segment) of the vertebrate photoreceptor. The mechanism underlying the ciliary targeting of PRPH2 and the etiology of cone dystrophy caused by PRPH2 mutations remain elusive. Here we show that th...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Otsu, Wataru, Hsu, Ya-Chu, Chuang, Jen-Zen, Sung, Ching-Hwa
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495125/
https://ncbi.nlm.nih.gov/pubmed/30819798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2811-18.2019
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