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CONFOUNDER ADJUSTMENT IN MULTIPLE HYPOTHESIS TESTING

We consider large-scale studies in which thousands of significance tests are performed simultaneously. In some of these studies, the multiple testing procedure can be severely biased by latent confounding factors such as batch effects and unmeasured covariates that correlate with both primary variab...

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Detalhes bibliográficos
Publicado no:Ann Stat
Main Authors: Wang, Jingshu, Zhao, Qingyuan, Hastie, Trevor, Owen, Art B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6706069/
https://ncbi.nlm.nih.gov/pubmed/31439967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1214/16-AOS1511
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