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CONFOUNDER ADJUSTMENT IN MULTIPLE HYPOTHESIS TESTING

We consider large-scale studies in which thousands of significance tests are performed simultaneously. In some of these studies, the multiple testing procedure can be severely biased by latent confounding factors such as batch effects and unmeasured covariates that correlate with both primary variab...

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Dettagli Bibliografici
Pubblicato in:Ann Stat
Autori principali: Wang, Jingshu, Zhao, Qingyuan, Hastie, Trevor, Owen, Art B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6706069/
https://ncbi.nlm.nih.gov/pubmed/31439967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1214/16-AOS1511
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