Neural Deletion of Glucose Transporter Isoform 3 Creates Distinct Postnatal and Adult Neurobehavioral Phenotypes

We created a neural-specific conditional murine glut3 (Slc2A3) deletion (glut3(flox/flox/nestin-Cre+)) to examine the effect of a lack of Glut3 on neurodevelopment. Compared with age-matched glut3(flox/flox) = WT and heterozygotes (glut3(flox/+/nestin-Cre+)), we found that a >90% reduction in mal...

Full description

Saved in:
Bibliographic Details
Published in:J Neurosci
Main Authors: Shin, Bo-Chul, Cepeda, Carlos, Estrada-Sánchez, Ana María, Levine, Michael S., Hodaei, Laya, Dai, Yun, Jung, Jai, Ganguly, Amit, Clark, Peter, Devaskar, Sherin U.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2018
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6706001/
https://ncbi.nlm.nih.gov/pubmed/30232223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0503-18.2018
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items