Neural Deletion of Glucose Transporter Isoform 3 Creates Distinct Postnatal and Adult Neurobehavioral Phenotypes

We created a neural-specific conditional murine glut3 (Slc2A3) deletion (glut3(flox/flox/nestin-Cre+)) to examine the effect of a lack of Glut3 on neurodevelopment. Compared with age-matched glut3(flox/flox) = WT and heterozygotes (glut3(flox/+/nestin-Cre+)), we found that a >90% reduction in mal...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:J Neurosci
Autores principales: Shin, Bo-Chul, Cepeda, Carlos, Estrada-Sánchez, Ana María, Levine, Michael S., Hodaei, Laya, Dai, Yun, Jung, Jai, Ganguly, Amit, Clark, Peter, Devaskar, Sherin U.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2018
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6706001/
https://ncbi.nlm.nih.gov/pubmed/30232223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0503-18.2018
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares