Trans-Modulation of the Somatostatin Type 2A Receptor Trafficking by Insulin-Regulated Aminopeptidase Decreases Limbic Seizures

Within the hippocampus, the major somatostatin (SRIF) receptor subtype, the sst2A receptor, is localized at postsynaptic sites of the principal neurons where it modulates neuronal activity. Following agonist exposure, this receptor rapidly internalizes and recycles slowly through the trans-Golgi net...

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Publicat a:J Neurosci
Autors principals: De Bundel, Dimitri, Fafouri, Assia, Csaba, Zsolt, Loyens, Ellen, Lebon, Sophie, El Ghouzzi, Vincent, Peineau, Stéphane, Vodjdani, Guilan, Kiagiadaki, Foteini, Aourz, Najat, Coppens, Jessica, Walrave, Laura, Portelli, Jeanelle, Vanderheyden, Patrick, Chai, Siew Yeen, Thermos, Kyriaki, Bernard, Véronique, Collingridge, Graham, Auvin, Stéphane, Gressens, Pierre, Smolders, Ilse, Dournaud, Pascal
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2015
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705451/
https://ncbi.nlm.nih.gov/pubmed/26311777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0476-15.2015
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