Inactivation of the Constitutively Active Ghrelin Receptor Attenuates Limbic Seizure Activity in Rodents

Ghrelin is a pleiotropic neuropeptide that has been recently implicated in epilepsy. Animal studies performed to date indicate that ghrelin has anticonvulsant properties; however, its mechanism of anticonvulsant action is unknown. Here we show that the anticonvulsant effects of ghrelin are mediated...

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Detalhes bibliográficos
Main Authors: Portelli, Jeanelle, Thielemans, Leen, Ver Donck, Luc, Loyens, Ellen, Coppens, Jessica, Aourz, Najat, Aerssens, Jeroen, Vermoesen, Katia, Clinckers, Ralph, Schallier, Anneleen, Michotte, Yvette, Moechars, Dieder, Collingridge, Graham L., Bortolotto, Zuner A., Smolders, Ilse
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3441926/
https://ncbi.nlm.nih.gov/pubmed/22669710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-012-0125-x
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