MuSK Frizzled-Like Domain Is Critical for Mammalian Neuromuscular Junction Formation and Maintenance

The muscle-specific kinase MuSK is one of the key molecules orchestrating neuromuscular junction (NMJ) formation. MuSK interacts with the Wnt morphogens, through its Frizzled-like domain (cysteine-rich domain [CRD]). Dysfunction of MuSK CRD in patients has been recently associated with the onset of...

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Опубликовано в: :J Neurosci
Главные авторы: Messéant, Julien, Dobbertin, Alexandre, Girard, Emmanuelle, Delers, Perrine, Manuel, Marin, Mangione, Francesca, Schmitt, Alain, Le Denmat, Dominique, Molgó, Jordi, Zytnicki, Daniel, Schaeffer, Laurent, Legay, Claire, Strochlic, Laure
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705368/
https://ncbi.nlm.nih.gov/pubmed/25810523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3381-14.2015
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