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Nicotinamide riboside promotes autolysosome clearance in preventing doxorubicin-induced cardiotoxicity
Doxorubicin (DOX) is widely used as a first-line chemotherapeutic drug for various malignancies. However, DOX causes severe cardiotoxicity, which limits its clinical uses. Oxidative stress is one of major contributors to DOX-induced cardiotoxicity. While autophagic flux serves as an important defens...
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| Publicado no: | Clin Sci (Lond) |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6705112/ https://ncbi.nlm.nih.gov/pubmed/31266854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20181022 |
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