Tanshinone IIA Restores Dynamic Balance of Autophagosome/Autolysosome in Doxorubicin-Induced Cardiotoxicity via Targeting Beclin1/LAMP1

Clinical use of the anti-cancer drug doxorubicin (DOX) is largely limited due to its severe cardiotoxicity. Dysregulation of autophagy is implicated in DOX-induced cardiotoxicity (DIC). Prior studies have indicated that Beclin1 and lysosomal-associated membrane proteins-1 (LAMP1) are critical mediat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Wang, Xiaoping, Li, Chun, Wang, Qiyan, Li, Weili, Guo, Dongqing, Zhang, Xuefeng, Shao, Mingyan, Chen, Xu, Ma, Lin, Zhang, Qian, Wang, Wei, Wang, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679133/
https://ncbi.nlm.nih.gov/pubmed/31261758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11070910
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados