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Parkin deficiency prevents chronic ethanol-induced hepatic lipid accumulation through β-catenin accumulation

BACKGROUND: Alcohol abuse and alcoholism lead to alcohol liver disease such as alcoholic fatty liver. Parkin is a component of the multiprotein E3 ubiquitin ligase complex and is associated with hepatic lipid accumulation. However, the role of parkin in ethanol-induced liver disease has not been rep...

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Dettagli Bibliografici
Pubblicato in:Cell Commun Signal
Autori principali: Lee, Dong Hun, Park, Mi Hee, Hwang, Chul Ju, Kim, Youngsoo, Hwang, Dae Yeon, Han, Sang Bae, Hong, Jin Tae
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704582/
https://ncbi.nlm.nih.gov/pubmed/31438968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0424-5
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