Parkin deficiency exacerbate ethanol-induced dopaminergic neurodegeneration by P38 pathway dependent inhibition of autophagy and mitochondrial function

Parkinson's disease (PD) is a neurodegenerative disease characterized by selective degeneration of dopaminergic neurons in the substantia nigra. Parkin (which encoded by Park2), an E3 ubiquitin ligase, is the most frequently mutated gene that has casually been linked to autosomal recessive earl...

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Опубликовано в: :Redox Biol
Главные авторы: Hwang, Chul Ju, Kim, Young Eun, Son, Dong Ju, Park, Mi Hee, Choi, Dong-Young, Park, Pil-Hoon, Hellström, Mats, Han, Sang-Bae, Oh, Ki-Wan, Park, Eun Kyung, Hong, Jin Tae
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2016
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226672/
https://ncbi.nlm.nih.gov/pubmed/28086194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.12.008
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