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Parkin deficiency exacerbate ethanol-induced dopaminergic neurodegeneration by P38 pathway dependent inhibition of autophagy and mitochondrial function

Parkinson's disease (PD) is a neurodegenerative disease characterized by selective degeneration of dopaminergic neurons in the substantia nigra. Parkin (which encoded by Park2), an E3 ubiquitin ligase, is the most frequently mutated gene that has casually been linked to autosomal recessive earl...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Hwang, Chul Ju, Kim, Young Eun, Son, Dong Ju, Park, Mi Hee, Choi, Dong-Young, Park, Pil-Hoon, Hellström, Mats, Han, Sang-Bae, Oh, Ki-Wan, Park, Eun Kyung, Hong, Jin Tae
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226672/
https://ncbi.nlm.nih.gov/pubmed/28086194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.12.008
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