Parkin deficiency exacerbate ethanol-induced dopaminergic neurodegeneration by P38 pathway dependent inhibition of autophagy and mitochondrial function

Parkinson's disease (PD) is a neurodegenerative disease characterized by selective degeneration of dopaminergic neurons in the substantia nigra. Parkin (which encoded by Park2), an E3 ubiquitin ligase, is the most frequently mutated gene that has casually been linked to autosomal recessive earl...

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Foilsithe in:Redox Biol
Main Authors: Hwang, Chul Ju, Kim, Young Eun, Son, Dong Ju, Park, Mi Hee, Choi, Dong-Young, Park, Pil-Hoon, Hellström, Mats, Han, Sang-Bae, Oh, Ki-Wan, Park, Eun Kyung, Hong, Jin Tae
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2016
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226672/
https://ncbi.nlm.nih.gov/pubmed/28086194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.12.008
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