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Impaired endothelial autophagy promotes liver fibrosis by aggravating the oxidative stress response during acute liver injury
BACKGROUND & AIMS: Endothelial dysfunction plays an essential role in liver injury, yet the phenotypic regulation of liver sinusoidal endothelial cells (LSECs) remains unknown. Autophagy is an endogenous protective system whose loss could undermine LSEC integrity and phenotype. The aim of our st...
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| Publicado no: | J Hepatol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6704477/ https://ncbi.nlm.nih.gov/pubmed/30367898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2018.10.015 |
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