Development of coupling controlled polymerizations by adapter-ligation in mate-pair sequencing for detection of various genomic variants in one single assay

The diversity of disease presentations warrants one single assay for detection and delineation of various genomic disorders. Herein, we describe a gel-free and biotin-capture-free mate-pair method through coupling Controlled Polymerizations by Adapter-Ligation (CP-AL). We first demonstrated the feas...

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Bibliografski detalji
Izdano u:DNA Res
Glavni autori: Dong, Zirui, Zhao, Xia, Li, Qiaoling, Yang, Zhenjun, Xi, Yang, Alexeev, Andrei, Shen, Hanjie, Wang, Ou, Ruan, Jie, Ren, Han, Wei, Hanmin, Qi, Xiaojuan, Li, Jiguang, Zhu, Xiaofan, Zhang, Yanyan, Dai, Peng, Kong, Xiangdong, Kirkconnell, Killeen, Alferov, Oleg, Giles, Shane, Yamtich, Jennifer, Kermani, Bahram G, Dong, Chao, Liu, Pengjuan, Mi, Zilan, Zhang, Wenwei, Xu, Xun, Drmanac, Radoje, Choy, Kwong Wai, Jiang, Yuan
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
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Full Papers
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704401/
https://ncbi.nlm.nih.gov/pubmed/31173071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/dnares/dsz011
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