Convection-Enhanced Delivery of Muscimol in Patients with Drug-Resistant Epilepsy

BACKGROUND: Minimally invasive therapies for drug-resistant epilepsy (DRE) have been advocated. A study of convection-enhanced delivery (CED) of muscimol, a GABA(A) receptor agonist, was previously completed in non-human primates. OBJECTIVE: To investigate the safety and anti-epileptic effects of in...

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Enregistré dans:
Détails bibliographiques
Publié dans:Neurosurgery
Auteurs principaux: Heiss, John D, Argersinger, Davis P, Theodore, William H, Butman, John A, Sato, Susumu, Khan, Omar I
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Research—Human—Clinical Trials
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704347/
https://ncbi.nlm.nih.gov/pubmed/30407567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuros/nyy480
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